Tertiary data analysis software for reporting germline and/or somatic genetic variants and biomarkers

The HUS Group requests tenders for Tertiary data analysis software for reporting germline and/or somatic genetic variants and biomarkers. The products are described in more detail in Appendix 4 to the call for tenders (Description of the Procurement). The estimated sample amounts per year on the Appendix 2 (Prices) and the Description of the Implementation Project (Appendix 6) also provide information on the scope of the procurement. Laboratory of Genetics at HUS Diagnostic Center is an SFS-EN ISO 15189:2013 accredited laboratory providing diagnostic genetic testing services mainly to patients at the city of Helsinki and the rest of Uusimaa province. The laboratory employs more than 100 professionals including 21 clinical laboratory geneticists and clinical geneticists. The services include analysis of both constitutional samples and malignancies. The laboratory uses mainly local sequencing capacity (e.g. Illumina NovaSeq 6000 and Ion Torrent S5 equipment) for its services. The laboratory also provides array CGH-based diagnostics using ISCA v2 array (Agilent Technologies) and RNA-based diagnostics using targeted and untargeted sequencing methods. HUS Laboratory of Genetics is seeking a data analysis software service for analyzing, interpreting the clinical significance, and reporting germline and somatic genetic alterations covering whole genome, whole exome and/or genes with the most common clinically relevant alterations (e.g. gene panels). This tender is intended for solutions covering germline (sub-section A) and/or somatic (sub-section B) diseases. Provider’s data analysis software does not have to be capable of both analysis types to respond to this tender. The procurement is divided into lots, as follows: - A. germline analysis - B. somatic analysis. The tenderers may leave a tender to one or more lots as they decide. The goal of this competitive procurement is to simplify the analysis software repertoire and make analysis of multiple data types possible with as few software as possible. This tender is not intended for interpretation services, but the laboratory will carry out sequencing, data analysis and interpretation in-house. RELATED CONTRACT PERIOD AND POSSIBLE OPTIONS See Agreement of the call for tenders for details. The agreement shall be valid for a fixed term of two (2) years, after which it shall continue for an indefinite period. The subject matter and requirements of the procurement are described in detail in the invitation to tender and its appendices.